A recent study suggests that erythritol, a popular low-calorie sugar substitute found in many sugar-free products such as energy drinks, protein bars, and snacks, may elevate the risk of vascular issues like stroke. While often marketed as a healthier alternative, the findings highlight potential dangers associated with its consumption.
Researchers from the University of Colorado Boulder’s Integrative Vascular Biology Laboratory conducted a study on erythritol’s impact on vascular health. They discovered that even a single serving of the sweetener, equivalent to that found in an energy drink, could disrupt brain and blood vessel health. The study, which was presented at the American Physiology Summit in Baltimore, suggests that erythritol may contribute to oxidative stress – a condition where unstable molecules damage cells – and interfere with nitric oxide production, a crucial component for proper blood circulation.
Auburn Berry, the lead author of the study, emphasized the need for more research to fully understand erythritol’s effects. “People should be mindful of the amount of erythritol they consume daily,” Berry stated, adding that although the compound is often touted as a healthy option, its impact on vascular health remains unclear.
The research team exposed human brain blood vessel cells to a solution of erythritol for three hours. The results showed significantly higher levels of oxidative stress compared to untreated cells. Berry explained that this heightened stress interferes with the production of nitric oxide, which is essential for blood vessels to expand and allow proper blood flow.
Experts in the field are also concerned about erythritol’s potential long-term effects. Dr. Thomas M. Holland, a scientist at Rush University Medical Center, noted that erythritol could accelerate cognitive decline. He explained that the sweetener causes a surge of harmful molecules called reactive oxygen species, which can lead to cellular damage, particularly in neural tissue. This damage may contribute to various diseases, including vascular and cognitive disorders.
The findings challenge the widespread perception of erythritol as a safe sugar alternative. Dr. Holland urged caution, particularly for individuals with existing risk factors for vascular disease, and highlighted the importance of moderation in erythritol consumption.
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