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Jase

Jase

Dr. Jase Booth is a dedicated diabetes specialist with over 15 years of experience in endocrinology. As a leading expert in diabetes management and care, he has helped countless patients achieve better health and improved quality of life through personalized treatment plans and cutting-edge research. In addition to her clinical practice, Dr. Booth serves as a senior editor at DiabetesCureHub.com, where he combines his medical expertise with his passion for education, providing valuable insights and updates on the latest advancements in diabetes treatment and prevention. His contributions to the field are recognized both nationally and internationally, making his a trusted voice in diabetes care.

Young-Onset Diabetes

What Causes Hyperglycemia In Type 2 Diabetes

2 型糖尿病(T2DM) 是一种慢性代谢紊乱,其特征是高血糖水平,这种情况称为高血糖症。与1 型糖尿病(人体无法产生胰岛素)不同,2 型糖尿病主要与胰岛素抵抗和胰岛素分泌最终下降有关。本文探讨了2 型糖尿病中高血糖的多方面原因,深入研究了导致其发展和进展的遗传、生理、生活方式和环境因素。 遗传因素 遗传易感性 遗传因素在 2 型糖尿病和随后的高血糖症的发展中起着重要作用。许多研究已经确定了与胰岛素抵抗和 β 细胞功能障碍(2 型糖尿病的两个标志性特征)相关的特定遗传变异。例如,TCF7L2 基因的多态性与 2 型糖尿病风险增加密切相关。该基因参与 Wnt 信号通路,影响胰腺 β...

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